Pharamacology Assignment Example | Topics and Well Written Essays - 1250 words

Pharamacology - Assignment Example Non sedating antihistamines are antihistamine drugs that can not enter brain and cause drowsiness in the patient and are normally used in treating the symptoms of reactions to stings and bites as well as allergies. The drugs work by blocking the activity of histamine produced by the body as part of the natural immunity. Compared to the sedating antihistamines, non sedating antihistamine drugs are generally more designed to be more selective for the peripheral H1 receptors rather than the cholinergic and central nervous system H1 receptors. This selectivity particularly makes the drugs to avoid sedation and other adverse reactions that may result when it is ingested to be used against allergic reactions (Tillement, Timmerman, Frossard and Levander, 2001, p.228). This paper critically discusses the issues that should be considered in the design of a tablet formulation for a non sedating antihistamine drug with a half life of 16 hours and an adult dose of 2mg per day as well as for a ch ildren liquid formulation (2-12 years old). One of the main factors to consider when formulating the new non sedating antihistamine drug is its disintegration time. This is particularly attributed to the fact that the new drug is expected to have a short half –life of 16 hours. For example, in order to ensure the effectiveness of the drug within its relatively short half-life, the tablet should be formulated in a way that it takes a short time for the tablet to break up into particles or granules once it has been ingested. According to Nelson (2007, p.46), this may be achieved by adding sufficient disintegrants, not using too much binder and avoiding compressing the tablets too hard in order to modify the disintegration and enhance a rapid effect of the drug before it reaches its half life. In addition, another issue related to the tablet formulation of the new non sedating antihistamine that should be

Should same sex marriage remain legal in the United Kingdom Research Paper

Should same sex marriage remain legal in the United Kingdom - Research Paper Example The research will be conducted using online materials and books on Gender and Sexuality. In 2010, Wales and England were moving towards legalization of same sex marriages. Scotland was given control over its marriages but in Northern Ireland, there were no plans for such legislations. Full recognition of gays, lesbian and bisexuals same sex couples in UK began in the 1960s where same sex sexual behaviour was decriminalized. In 2005, same sex couples were able to enter into civil partnerships. Civil partnerships are indistinguishable from opposite sex marriage in terms of rights. This means that they grant the same privileges, obligations, and rights to the couples. Lee (2010, pp, 18) supported this view. According to Piercceson (2014, pp, 22-25) in 2009 public support had risen to 61%. Politicians were debating on changing the definition of marriage to allow all couples to marry. In 2011, the media reported that the government would allow gay church marriage. In 2013, there was a bill to legalise same sex marriage in England and Wales and in July 2013 the House of Lords approved the Marriage (Same sex Couples) Act. Couples of the same sex were able to register and marry and this resulted in England and Wales recognising same sex marriages. Same sex marriages should remain legal in United Kingdom to avoid violation of human rights. The United Nations of Human rights states that all rights are inherent to all human beings regardless of nationality, gender and religious views etc .Every human being has the same right to do as they please as long as it does not cause harm to another person. Same sex marriages are a matter of civil and equal rights and the decision to remain married should remain with the two individuals in the union. Most people are usually not comfortable with same sex relationships however; the dignity of such couples should be respected. Therefore, the law should remain to avoid a severe violation of